Bone Marrow Mesenchymal Stem Cells in a Three-Dimensional Gelatin Sponge Scaffold Attenuate Inflammation, Promote Angiogenesis, and Reduce Cavity Formation in Experimental Spinal Cord Injury

Three-dimensional (3D) gelatin sponge (GS) scaffolds were constructed by ensheathing GS with a thin film of poly-(lactide- co -glycolide) (PLGA). Rat bone marrow-derived mesenchymal stem cells (MSCs) were isolated, cultured, and then seeded to the scaffolds. Distribution of cells and cell growth, su...

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Bibliographic Details
Main Authors: Xiang Zeng, Yuan-Shan Zeng M.D., Ph.D., Yuan-Huan Ma, Li-Ya Lu, Bao-Ling Du, Wei Zhang, Yan Li, Wood Yee Chan Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2011-12-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368911X566181