Insulin-Like Growth Factor I Prevents Cellular Aging via Activation of Mitophagy

Insulin-Like Growth Factor I Prevents Cellular Aging via Activation of Mitophagy

Mitochondrial dysfunction is a hallmark of cellular aging. Mitophagy is a critical mitochondrial quality control mechanism that removes dysfunctional mitochondria and contributes to cell survival. Insulin-like growth factor 1 (IGF-1) promotes survival of smooth muscle cells (SMCs), but its potential...

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Bibliographic Details
Main Authors:	Xuwei Hou, Zhaohui Li, Yusuke Higashi, Patrice Delafontaine, Sergiy Sukhanov
Format:	Article
Language:	English
Published:	Hindawi Limited 2020-01-01
Series:	Journal of Aging Research
Online Access:	http://dx.doi.org/10.1155/2020/4939310

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