Osteopontin: A Potential Biomarker for Successful Bee Venom Immunotherapy and a Potential Molecule for Inhibiting IgE-mediated Allergic Responses

Venom immunotherapy (VIT) is proven to be curative for insect allergy, but the mechanisms and the biomarkers associated with clinical efficacy remain elusive. We report herein the discovery of a leading candidate biomarker, osteopontin (OPN), for VIT. From cDNA microarray and clustering analyses, an...

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Bibliographic Details
Main Authors: Satoshi Konno, Nobuyuki Hizawa, Masaharu Nishimura, Shau-Ku Huang
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Allergology International
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015309898