Human Uterine Biopsy: Research Value and Common Pitfalls

The human uterus consists of the inner endometrium, the myometrium, and the outer serosa. Knowledge of the function of the uterus in health and disease is relevant to reproduction, fertility, embryology, gynaecology, endocrinology, and oncology. Research performed on uterine biopsies is essential to...

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Main Authors: Alison Maclean, Areege Kamal, Meera Adishesh, Rafah Alnafakh, Nicola Tempest, Dharani K. Hapangama
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:International Journal of Reproductive Medicine
Online Access:http://dx.doi.org/10.1155/2020/9275360
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spelling doaj-c1ceb3792b3046daa0de23afafe906a62020-11-25T02:04:34ZengHindawi LimitedInternational Journal of Reproductive Medicine2356-71042314-57572020-01-01202010.1155/2020/92753609275360Human Uterine Biopsy: Research Value and Common PitfallsAlison Maclean0Areege Kamal1Meera Adishesh2Rafah Alnafakh3Nicola Tempest4Dharani K. Hapangama5Department of Women’s and Children’s Health, Institute of Translational Medicine, University of Liverpool, Member of the Liverpool Health Partnership, Liverpool Women’s NHS Foundation Trust, Liverpool L8 7SS, UKDepartment of Women’s and Children’s Health, Institute of Translational Medicine, University of Liverpool, Member of the Liverpool Health Partnership, Liverpool Women’s NHS Foundation Trust, Liverpool L8 7SS, UKDepartment of Women’s and Children’s Health, Institute of Translational Medicine, University of Liverpool, Member of the Liverpool Health Partnership, Liverpool Women’s NHS Foundation Trust, Liverpool L8 7SS, UKDepartment of Women’s and Children’s Health, Institute of Translational Medicine, University of Liverpool, Member of the Liverpool Health Partnership, Liverpool Women’s NHS Foundation Trust, Liverpool L8 7SS, UKDepartment of Women’s and Children’s Health, Institute of Translational Medicine, University of Liverpool, Member of the Liverpool Health Partnership, Liverpool Women’s NHS Foundation Trust, Liverpool L8 7SS, UKDepartment of Women’s and Children’s Health, Institute of Translational Medicine, University of Liverpool, Member of the Liverpool Health Partnership, Liverpool Women’s NHS Foundation Trust, Liverpool L8 7SS, UKThe human uterus consists of the inner endometrium, the myometrium, and the outer serosa. Knowledge of the function of the uterus in health and disease is relevant to reproduction, fertility, embryology, gynaecology, endocrinology, and oncology. Research performed on uterine biopsies is essential to further the current understanding of human uterine biology. This brief review explores the value of the uterine biopsy in gynaecological and human fertility research and explores the common problems encountered when analysing data generated from different types of uterine biopsies, with the aim of improving the quality, reproducibility, and clinical translatability of future research.http://dx.doi.org/10.1155/2020/9275360
collection DOAJ
language English
format Article
sources DOAJ
author Alison Maclean
Areege Kamal
Meera Adishesh
Rafah Alnafakh
Nicola Tempest
Dharani K. Hapangama
spellingShingle Alison Maclean
Areege Kamal
Meera Adishesh
Rafah Alnafakh
Nicola Tempest
Dharani K. Hapangama
Human Uterine Biopsy: Research Value and Common Pitfalls
International Journal of Reproductive Medicine
author_facet Alison Maclean
Areege Kamal
Meera Adishesh
Rafah Alnafakh
Nicola Tempest
Dharani K. Hapangama
author_sort Alison Maclean
title Human Uterine Biopsy: Research Value and Common Pitfalls
title_short Human Uterine Biopsy: Research Value and Common Pitfalls
title_full Human Uterine Biopsy: Research Value and Common Pitfalls
title_fullStr Human Uterine Biopsy: Research Value and Common Pitfalls
title_full_unstemmed Human Uterine Biopsy: Research Value and Common Pitfalls
title_sort human uterine biopsy: research value and common pitfalls
publisher Hindawi Limited
series International Journal of Reproductive Medicine
issn 2356-7104
2314-5757
publishDate 2020-01-01
description The human uterus consists of the inner endometrium, the myometrium, and the outer serosa. Knowledge of the function of the uterus in health and disease is relevant to reproduction, fertility, embryology, gynaecology, endocrinology, and oncology. Research performed on uterine biopsies is essential to further the current understanding of human uterine biology. This brief review explores the value of the uterine biopsy in gynaecological and human fertility research and explores the common problems encountered when analysing data generated from different types of uterine biopsies, with the aim of improving the quality, reproducibility, and clinical translatability of future research.
url http://dx.doi.org/10.1155/2020/9275360
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