A highly functional synthetic phage display library containing over 40 billion human antibody clones.

Several synthetic antibody phage display libraries have been created and used for the isolation of human monoclonal antibodies. The performance of antibody libraries, which is usually measured in terms of their ability to yield high-affinity binding specificities against target proteins of interest,...

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Bibliographic Details
Main Authors: Marcel Weber, Emil Bujak, Alessia Putelli, Alessandra Villa, Mattia Matasci, Laura Gualandi, Teresa Hemmerle, Sarah Wulhfard, Dario Neri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4065035?pdf=render