Resistance to dopamine agonists and somatostatin analogues in pituitary tumors: focus on cytoskeleton involvement

Resistance to dopamine agonists and somatostatin analogues in pituitary tumors: focus on cytoskeleton involvement

Pituitary tumors, that origin from excessive proliferation of a specific subtype of pituitary cell, are mostly benign tumors, but may cause significant morbidity in affected patients, including visual and neurologic manifestations from mass-effect, or endocrine syndromes caused by hormone hypersecre...

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Bibliographic Details
Main Authors: Erika ePeverelli, Donatella eTreppiedi, Elena eGiardino, Eleonora eVitali, Andrea G Lania, Giovanna eMantovani
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Endocrinology
Subjects:
Dopamine
Somatostatin
pituitary tumors
DRD2
filamin A
Pharmacological resistance
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2015.00187/full

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