Diagnostic Ability of Methods Depicting Distress of Tumor-Bearing Mice

Diagnostic Ability of Methods Depicting Distress of Tumor-Bearing Mice

Subcutaneous tumor models in mice are the most commonly used experimental animal models in cancer research. To improve animal welfare and the quality of scientific studies, the distress of experimental animals needs to be minimized. For this purpose, one must assess the diagnostic ability of readout...

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Bibliographic Details
Main Authors: Wentao Xie, Marcel Kordt, Rupert Palme, Eberhard Grambow, Brigitte Vollmar, Dietmar Zechner
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Animals
Subjects:
animal model
animal welfare
xenograft models
in vivo
3Rs
Online Access:https://www.mdpi.com/2076-2615/11/8/2155

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