Resveratrol Activates Autophagy via the AKT/mTOR Signaling Pathway to Improve Cognitive Dysfunction in Rats With Chronic Cerebral Hypoperfusion

Resveratrol Activates Autophagy via the AKT/mTOR Signaling Pathway to Improve Cognitive Dysfunction in Rats With Chronic Cerebral Hypoperfusion

Chronic cerebral hypoperfusion (CCH) is a main cause of vascular dementia and is also an etiological factor of neurological diseases and mental disorders. However, few treatments are available for CCH, and new medications are needed. In the present study, we employed a rat model of CCH that was base...

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Bibliographic Details
Main Authors: Nan Wang, Jinting He, Chengliang Pan, Jiaoqi Wang, Ming Ma, Xinxiu Shi, Zhongxin Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Neuroscience
Subjects:
resveratrol
AKT
mTOR
cognitive dysfunction
chronic cerebral hypoperfusion
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00859/full

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