GSH-C4 Acts as Anti-inflammatory Drug in Different Models of Canonical and Cell Autonomous Inflammation Through NFκB Inhibition

GSH-C4 Acts as Anti-inflammatory Drug in Different Models of Canonical and Cell Autonomous Inflammation Through NFκB Inhibition

An imbalance in GSH/GSSG ratio represents a triggering event in pro-inflammatory cytokine production and inflammatory response. However, the molecular mechanism(s) through which GSH regulates macrophage and cell autonomous inflammation remains not deeply understood. Here, we investigated the effects...

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Bibliographic Details
Main Authors: Dolores Limongi, Sara Baldelli, Paola Checconi, Maria Elena Marcocci, Giovanna De Chiara, Alessandra Fraternale, Mauro Magnani, Maria Rosa Ciriolo, Anna Teresa Palamara
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
glutathione
macrophage
adipocytes
myocytes
cytokine
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00155/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00155/full

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