A synthetic model of human beta-thalassemia erythropoiesis using CD34+ cells from healthy adult donors.
Based upon the lack of clinical samples available for research in many laboratories worldwide, a significant gap exists between basic and clinical studies of beta-thalassemia major. To bridge this gap, we developed an artificially engineered model for human beta thalassemia by knocking down beta-glo...
Main Authors: | Y Terry Lee, Ki Soon Kim, Colleen Byrnes, Jaira F de Vasconcellos, Seung-Jae Noh, Antoinette Rabel, Emily R Meier, Jeffery L Miller |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3704632?pdf=render |
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