Apoptosis in cancer: from pathogenesis to discovery of advanced selective Bcl-2 family inhibitors

Apoptosis in cancer: from pathogenesis to discovery of advanced selective Bcl-2 family inhibitors

Cancer is a genetic disease characterized by two features: unregulated cell growth and tissue invasion (metastasis). It can be viewed as the result of a succession of genetic changes during which a normal cell is transformed into a malignant one. Evasion of cell death, apoptosis, is one of the essen...

Full description

Bibliographic Details
Main Authors: Samaa Abbas, Nermin S. Abdou, Deena S. Lasheen, Dalal A. Abou El Ella
Format: Article
Language:English
Published: Ain Shams University 2019-06-01
Series: Archives of Pharmaceutical Sciences Ain Shams University
Subjects:
apoptosis
Bcl-2
Extrinsic pathway
Intrinsic pathway
Caspase
BH3
Online Access:https://aps.journals.ekb.eg/article_29016.html

Similar Items

Similar Items