RNA-guided assembly of Rev-RRE nuclear export complexes

RNA-guided assembly of Rev-RRE nuclear export complexes

HIV replication requires nuclear export of unspliced and singly spliced viral transcripts. Although a unique RNA structure has been proposed for the Rev-response element (RRE) responsible for viral mRNA export, how it recruits multiple HIV Rev proteins to form an export complex has been unclear. We...

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Bibliographic Details
Main Authors: Yun Bai, Akshay Tambe, Kaihong Zhou, Jennifer A Doudna
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-08-01
Series:eLife
Subjects:
SHAPE-Seq
HIV RRE-Rev complex
RNA nuclear export
Online Access:https://elifesciences.org/articles/03656

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