Mouse models of diet-induced nonalcoholic steatohepatitis reproduce the heterogeneity of the human disease.

Mouse models of diet-induced nonalcoholic steatohepatitis reproduce the heterogeneity of the human disease.

Non-alcoholic steatohepatitis (NASH), the potentially progressive form of nonalcoholic fatty liver disease (NAFLD), is the pandemic liver disease of our time. Although there are several animal models of NASH, consensus regarding the optimal model is lacking. We aimed to compare features of NASH in t...

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Bibliographic Details
Main Authors: Mariana Verdelho Machado, Gregory Alexander Michelotti, Guanhua Xie, Thiago Almeida Pereira, Jerome Boursier, Brittany Bohnic, Cynthia D Guy, Anna Mae Diehl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4446215?pdf=render

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