Structural basis of inhibition of a transporter from Staphylococcus aureus, NorC, through a single-domain camelid antibody
Sushant Kumar et. al. report the 3.6 Å resolution crystal structure of NorC, a 14-transmembrane major facilitator superfamily member that is implicated in fluoroquinolone resistance in drug-resistant Staphylococcus aureus strains. The NorC structure was determined in complex with a single-domain cam...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-07-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-02357-x |