The role of IL-1β and TNF-α in intervertebral disc degeneration

The role of IL-1β and TNF-α in intervertebral disc degeneration

Low back pain (LBP), a prevalent and costly disease around the world, is predominantly caused by intervertebral disc (IVD) degeneration (IDD). LBP also presents a substantial burden to public health and the economy. IDD is mainly caused by aging, trauma, genetic susceptibility, and other factors. It...

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Bibliographic Details
Main Authors: Yongjie Wang, Mingxue Che, Jingguo Xin, Zhi Zheng, Jiangbi Li, Shaokun Zhang
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
IL-1β
TNF-α
Intervertebral disc degeneration
Cytokines
Low back pain
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220308532

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