Functional Characterization of the Oxantel-Sensitive Acetylcholine Receptor from <i>Trichuris muris</i>

Functional Characterization of the Oxantel-Sensitive Acetylcholine Receptor from <i>Trichuris muris</i>

The human whipworm, <i>Trichuris trichiura</i>, is estimated to infect 289.6 million people globally. Control of human trichuriasis is a particular challenge, as most anthelmintics have a limited single-dose efficacy, with the striking exception of the narrow-spectrum anthelmintic, oxant...

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Bibliographic Details
Main Authors: Tina V. A. Hansen, Richard K. Grencis, Mohamed Issouf, Cédric Neveu, Claude L. Charvet
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pharmaceuticals
Subjects:
<i>Trichuris</i>
antiparasitic drugs
oxantel
nAChR
helminths
electrophysiology
Online Access:https://www.mdpi.com/1424-8247/14/7/698

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