Inhibition of chondrosarcoma growth by mTOR inhibitor in an in vivo syngeneic rat model.

Inhibition of chondrosarcoma growth by mTOR inhibitor in an in vivo syngeneic rat model.

BACKGROUND: Chondrosarcomas are the second most frequent primary malignant type of bone tumor. No effective systemic treatment has been identified in advanced or adjuvant phases for chondrosarcoma. The aim of the present study was to determine the antitumor effects of doxorubicin and everolimus, an...

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Bibliographic Details
Main Authors: Jennifer Perez, Anne Valérie Decouvelaere, Thomas Pointecouteau, Daniel Pissaloux, Jean Philippe Michot, Anthony Besse, Jean Yves Blay, Aurélie Dutour
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3384598?pdf=render

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