Prostaglandin D2 and Interleukin-5 Reduce Crth2 Surface Expression on Human Eosinophils

Prostaglandin D2 and Interleukin-5 Reduce Crth2 Surface Expression on Human Eosinophils

Background: Recently, a second prostaglandin D2 (PGD2) receptor, chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2), was identified. Because PGD2 was reported to have chemotactic activity on eosinophils, CRTH2 expressed on eosinophils attracted interest as a receptor associa...

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Bibliographic Details
Main Authors: Kazuyuki Hamada, Yoshiyuki Yamada, Yumiko Kamada, Shigeharu Ueki, Kazutoshi Yamaguchi, Hajime Oyamada, Miyoshi Fujita, Atsuko Usami, Takahito Chiba, Akira Kanda, Hiroyuki Kayaba, Junichi Chihara
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Allergology International
Subjects:
CRTH2
eosinophils
interferon-γ
interleukin-4
interleukin-5
prostaglandin D2
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015311138

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