Differential Response of Gestational Tissues to TLR3 Viral Priming Prior to Exposure to Bacterial TLR2 and TLR2/6 Agonists

Differential Response of Gestational Tissues to TLR3 Viral Priming Prior to Exposure to Bacterial TLR2 and TLR2/6 Agonists

Background: Infection/inflammation is an important causal factor in spontaneous preterm birth (sPTB). Most mechanistic studies have concentrated on the role of bacteria, with limited focus on the role of viruses in sPTB. Murine studies support a potential multi-pathogen aetiology in which a double o...

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Bibliographic Details
Main Authors: Zahirrah B. M. Rasheed, Yun S. Lee, Sung H. Kim, Ranjit K. Rai, Camino S. M. Ruano, Eberechi Anucha, Mark H. F. Sullivan, David A. MacIntyre, Phillip R. Bennett, Lynne Sykes
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
toll like receptor
viral priming
preterm labour
pregnancy
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01899/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01899/full

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