Optimization of a one-step heat-inducible in vivo mini DNA vector production system.

Optimization of a one-step heat-inducible in vivo mini DNA vector production system.

While safer than their viral counterparts, conventional circular covalently closed (CCC) plasmid DNA vectors offer a limited safety profile. They often result in the transfer of unwanted prokaryotic sequences, antibiotic resistance genes, and bacterial origins of replication that may lead to unwante...

Full description

Bibliographic Details
Main Authors: Nafiseh Nafissi, Chi Hong Sum, Shawn Wettig, Roderick A Slavcev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3930727?pdf=render

Similar Items

Similar Items