In vitro model of the blood-brain barrier established by co-culture of primary cerebral microvascular endothelial and astrocyte cells

In vitro model of the blood-brain barrier established by co-culture of primary cerebral microvascular endothelial and astrocyte cells

Drugs for the treatment and prevention of nervous system diseases must permeate the blood-brain barrier to take effect. In vitro models of the blood-brain barrier are therefore important in the investigation of drug permeation mechanisms. However, to date, no unified method has been described for es...

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Bibliographic Details
Main Authors: Yan Wang, Ning Wang, Biao Cai, Guang-yun Wang, Jing Li, Xing-xing Piao
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; blood-brain barrier; astrocytes; brain microvascular endothelial cells; permeability; co-culture; Transwell chamber; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=12;spage=2011;epage=2017;aulast=Wang

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=12;spage=2011;epage=2017;aulast=Wang

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