In silico ADME and Toxicity Prediction of Ceftazidime and Its Impurities

In silico ADME and Toxicity Prediction of Ceftazidime and Its Impurities

To improve the quality control of drugs, we predicted the absorption, distribution, metabolism, excretion, and toxicity (ADMET) of ceftazidime (CAZ) and its impurities via in silico methods. We used three types of quantitative structure-activity relationship and docking software for precise predicti...

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Bibliographic Details
Main Authors: Ying Han, Jingpu Zhang, Chang Qin Hu, Xia Zhang, Bufang Ma, Peipei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Pharmacology
Subjects:
ceftazidime
impurity
toxicity
docking
ADME
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00434/full

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