Effects of the inlet conditions and blood models on accurate prediction of hemodynamics in the stented coronary arteries

Hemodynamics altered by stent implantation is well-known to be closely related to in-stent restenosis. Computational fluid dynamics (CFD) method has been used to investigate the hemodynamics in stented arteries in detail and help to analyze the performances of stents. In this study, blood models wit...

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Main Authors: Yongfei Jiang, Jun Zhang, Wanhua Zhao
Format: Article
Language:English
Published: AIP Publishing LLC 2015-05-01
Series:AIP Advances
Online Access:http://dx.doi.org/10.1063/1.4919937
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spelling doaj-c1275d5f01114d62a7a256ee1a5e5a172020-11-24T21:47:53ZengAIP Publishing LLCAIP Advances2158-32262015-05-0155057109057109-910.1063/1.4919937009505ADVEffects of the inlet conditions and blood models on accurate prediction of hemodynamics in the stented coronary arteriesYongfei Jiang0Jun Zhang1Wanhua Zhao2School of Mechanical Engineering, Xi’an Jiaotong University, Xi’an, 710049, People’s Republic of ChinaSchool of Mechanical Engineering, Xi’an Jiaotong University, Xi’an, 710049, People’s Republic of ChinaSchool of Mechanical Engineering, Xi’an Jiaotong University, Xi’an, 710049, People’s Republic of ChinaHemodynamics altered by stent implantation is well-known to be closely related to in-stent restenosis. Computational fluid dynamics (CFD) method has been used to investigate the hemodynamics in stented arteries in detail and help to analyze the performances of stents. In this study, blood models with Newtonian or non-Newtonian properties were numerically investigated for the hemodynamics at steady or pulsatile inlet conditions respectively employing CFD based on the finite volume method. The results showed that the blood model with non-Newtonian property decreased the area of low wall shear stress (WSS) compared with the blood model with Newtonian property and the magnitude of WSS varied with the magnitude and waveform of the inlet velocity. The study indicates that the inlet conditions and blood models are all important for accurately predicting the hemodynamics. This will be beneficial to estimate the performances of stents and also help clinicians to select the proper stents for the patients.http://dx.doi.org/10.1063/1.4919937
collection DOAJ
language English
format Article
sources DOAJ
author Yongfei Jiang
Jun Zhang
Wanhua Zhao
spellingShingle Yongfei Jiang
Jun Zhang
Wanhua Zhao
Effects of the inlet conditions and blood models on accurate prediction of hemodynamics in the stented coronary arteries
AIP Advances
author_facet Yongfei Jiang
Jun Zhang
Wanhua Zhao
author_sort Yongfei Jiang
title Effects of the inlet conditions and blood models on accurate prediction of hemodynamics in the stented coronary arteries
title_short Effects of the inlet conditions and blood models on accurate prediction of hemodynamics in the stented coronary arteries
title_full Effects of the inlet conditions and blood models on accurate prediction of hemodynamics in the stented coronary arteries
title_fullStr Effects of the inlet conditions and blood models on accurate prediction of hemodynamics in the stented coronary arteries
title_full_unstemmed Effects of the inlet conditions and blood models on accurate prediction of hemodynamics in the stented coronary arteries
title_sort effects of the inlet conditions and blood models on accurate prediction of hemodynamics in the stented coronary arteries
publisher AIP Publishing LLC
series AIP Advances
issn 2158-3226
publishDate 2015-05-01
description Hemodynamics altered by stent implantation is well-known to be closely related to in-stent restenosis. Computational fluid dynamics (CFD) method has been used to investigate the hemodynamics in stented arteries in detail and help to analyze the performances of stents. In this study, blood models with Newtonian or non-Newtonian properties were numerically investigated for the hemodynamics at steady or pulsatile inlet conditions respectively employing CFD based on the finite volume method. The results showed that the blood model with non-Newtonian property decreased the area of low wall shear stress (WSS) compared with the blood model with Newtonian property and the magnitude of WSS varied with the magnitude and waveform of the inlet velocity. The study indicates that the inlet conditions and blood models are all important for accurately predicting the hemodynamics. This will be beneficial to estimate the performances of stents and also help clinicians to select the proper stents for the patients.
url http://dx.doi.org/10.1063/1.4919937
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AT junzhang effectsoftheinletconditionsandbloodmodelsonaccuratepredictionofhemodynamicsinthestentedcoronaryarteries
AT wanhuazhao effectsoftheinletconditionsandbloodmodelsonaccuratepredictionofhemodynamicsinthestentedcoronaryarteries
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