NAMPT and BMAL1 Are Independently Involved in the Palmitate-Mediated Induction of Neuroinflammation in Hypothalamic Neurons

Obesity is a prominent metabolic disease that predisposes individuals to multiple comorbidities, including type 2 diabetes mellitus, cardiovascular diseases, and cancer. Elevated circulating levels of fatty acids contribute to the development of obesity, in part, by targeting the hypothalamus. Palmi...

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Bibliographic Details
Main Authors: Andy Tran, Wenyuan He, Nan Jiang, Jim T. C. Chen, Denise D. Belsham
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00351/full