Lack of Diaph3 relaxes the spindle checkpoint causing the loss of neural progenitors

Molecular mechanisms that control the division of neural progenitor cells are only partially understood. Here the authors show that Diaph3 is critical for spindle checkpoint activity in cortical progenitor cells as the loss of Diaph3 leads to apoptosis of progenitor cells and eventually results in m...

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Bibliographic Details
Main Authors: Devid Damiani, André M. Goffinet, Arthur Alberts, Fadel Tissir
Format: Article
Language:English
Published: Nature Publishing Group 2016-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13509