SH2-inositol phosphatase 1 negatively influences early megakaryocyte progenitors.

SH2-inositol phosphatase 1 negatively influences early megakaryocyte progenitors.

The SH2-containing-5'inositol phosphatase-1 (SHIP) influences signals downstream of cytokine/chemokine receptors that play a role in megakaryocytopoiesis, including thrombopoietin, stromal-cell-derived-Factor-1/CXCL-12 and interleukin-3. We hypothesize that SHIP might control megakaryocytopoies...

Full description

Bibliographic Details
Main Authors: Lia E Perez, Caroline Desponts, Nancy Parquet, William G Kerr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2569203?pdf=render

Similar Items

Similar Items