Increase in the diagnosis of mycobacteremia after the implementation of semi-automated blood culture at a Brazilian public health laboratory

Abstract INTRODUCTION The prevalence of hematogenous dissemination of mycobacteria is high in immunosuppressed patients. The isolation of mycobacteria in culture remains the standard procedure. METHODS This is a cross-sectional study based on the results of solid (Löwenstein-Jensen medium) and s...

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Main Authors: Adelaide Fernandes Costa, Sueli Lemes de Ávila Alves, Ivanísio Gomes de Santana, Disley Xavier Rodrigues Dias, Edna Joana Claudio Manrique
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2019-04-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100637&lng=en&tlng=en
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spelling doaj-c1153a2d21084dd2944f42d08e5541b32020-11-25T00:30:02ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492019-04-0152010.1590/0037-8682-0267-2018S0037-86822019000100637Increase in the diagnosis of mycobacteremia after the implementation of semi-automated blood culture at a Brazilian public health laboratoryAdelaide Fernandes CostaSueli Lemes de Ávila AlvesIvanísio Gomes de SantanaDisley Xavier Rodrigues DiasEdna Joana Claudio ManriqueAbstract INTRODUCTION The prevalence of hematogenous dissemination of mycobacteria is high in immunosuppressed patients. The isolation of mycobacteria in culture remains the standard procedure. METHODS This is a cross-sectional study based on the results of solid (Löwenstein-Jensen medium) and semi-automated liquid (BACTEC 9240) blood cultures, obtained from the Lacen-GO database. RESULTS The implementation of a semi-automated procedure resulted in an increase of 61.5% and 350.0% in the positive results for Mycobacterium tuberculosis complex and nontuberculous mycobacteria, respectively. This technique also accelerated the detection of positive results. CONCLUSIONS Semi-automated liquid blood culture showed a better performance in the diagnosis of mycobacteremia.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100637&lng=en&tlng=enBlood cultureImmunosuppressionMycobacteria
collection DOAJ
language English
format Article
sources DOAJ
author Adelaide Fernandes Costa
Sueli Lemes de Ávila Alves
Ivanísio Gomes de Santana
Disley Xavier Rodrigues Dias
Edna Joana Claudio Manrique
spellingShingle Adelaide Fernandes Costa
Sueli Lemes de Ávila Alves
Ivanísio Gomes de Santana
Disley Xavier Rodrigues Dias
Edna Joana Claudio Manrique
Increase in the diagnosis of mycobacteremia after the implementation of semi-automated blood culture at a Brazilian public health laboratory
Revista da Sociedade Brasileira de Medicina Tropical
Blood culture
Immunosuppression
Mycobacteria
author_facet Adelaide Fernandes Costa
Sueli Lemes de Ávila Alves
Ivanísio Gomes de Santana
Disley Xavier Rodrigues Dias
Edna Joana Claudio Manrique
author_sort Adelaide Fernandes Costa
title Increase in the diagnosis of mycobacteremia after the implementation of semi-automated blood culture at a Brazilian public health laboratory
title_short Increase in the diagnosis of mycobacteremia after the implementation of semi-automated blood culture at a Brazilian public health laboratory
title_full Increase in the diagnosis of mycobacteremia after the implementation of semi-automated blood culture at a Brazilian public health laboratory
title_fullStr Increase in the diagnosis of mycobacteremia after the implementation of semi-automated blood culture at a Brazilian public health laboratory
title_full_unstemmed Increase in the diagnosis of mycobacteremia after the implementation of semi-automated blood culture at a Brazilian public health laboratory
title_sort increase in the diagnosis of mycobacteremia after the implementation of semi-automated blood culture at a brazilian public health laboratory
publisher Sociedade Brasileira de Medicina Tropical (SBMT)
series Revista da Sociedade Brasileira de Medicina Tropical
issn 1678-9849
publishDate 2019-04-01
description Abstract INTRODUCTION The prevalence of hematogenous dissemination of mycobacteria is high in immunosuppressed patients. The isolation of mycobacteria in culture remains the standard procedure. METHODS This is a cross-sectional study based on the results of solid (Löwenstein-Jensen medium) and semi-automated liquid (BACTEC 9240) blood cultures, obtained from the Lacen-GO database. RESULTS The implementation of a semi-automated procedure resulted in an increase of 61.5% and 350.0% in the positive results for Mycobacterium tuberculosis complex and nontuberculous mycobacteria, respectively. This technique also accelerated the detection of positive results. CONCLUSIONS Semi-automated liquid blood culture showed a better performance in the diagnosis of mycobacteremia.
topic Blood culture
Immunosuppression
Mycobacteria
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100637&lng=en&tlng=en
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