Ubiquitination is involved in secondary growth, not initial formation of polyglutamine protein aggregates in <it>C. elegans</it>
<p>Abstract</p> <p>Background</p> <p>Protein misfolding and subsequent aggregation are hallmarks of several human diseases. The cell has a variety of mechanisms for coping with misfolded protein stress, including ubiquitin-mediated protein degradation. In fact, the pres...
Main Authors: | Skibinski Gregory A, Boyd Lynn |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-04-01
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Series: | BMC Cell Biology |
Online Access: | http://www.biomedcentral.com/1471-2121/13/10 |
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