The role of ceramide and SEW 2871 in the transcription of enzymes involved in amyloid b precursor protein metabolism in an experimental model of Alzheimer’s disease
Alzheimer’s disease (AD) is characterized by alterations of amyloid precursor protein (APP) metabolism, accumulation of amyloid peptides (A), hyperphosphorylation of Tau proteins and also by sphingolipids disturbances. These changes lead to oxidative stress, mitochondria dysfunction, synaptic los...
Main Authors: | Kinga Czubowicz, Sylwia Wójtowicz, Przemysław Leonard Wencel, Robert Piotr Strosznajder |
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Format: | Article |
Language: | English |
Published: |
Termedia Publishing House
2018-09-01
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Series: | Folia Neuropathologica |
Subjects: | |
Online Access: | https://www.termedia.pl/The-role-of-ceramide-and-SEW-2871-in-the-transcription-of-enzymes-involved-in-amyloid-b-precursor-protein-metabolism-in-an-experimental-model-of-Alzheimer-s-disease,20,33884,1,1.html |
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