The role of ceramide and SEW 2871 in the transcription of enzymes involved in amyloid b precursor protein metabolism in an experimental model of Alzheimer’s disease

The role of ceramide and SEW 2871 in the transcription of enzymes involved in amyloid b precursor protein metabolism in an experimental model of Alzheimer’s disease

Alzheimer’s disease (AD) is characterized by alterations of amyloid precursor protein (APP) metabolism, accumulation of amyloid  peptides (A), hyperphosphorylation of Tau proteins and also by sphingolipids disturbances. These changes lead to oxidative stress, mitochondria dysfunction, synaptic los...

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Bibliographic Details
Main Authors: Kinga Czubowicz, Sylwia Wójtowicz, Przemysław Leonard Wencel, Robert Piotr Strosznajder
Format: Article
Language:English
Published: Termedia Publishing House 2018-09-01
Series:Folia Neuropathologica
Subjects:
amyloid  peptide
ceramide
sphingosine-1-phosphate
secretases
sirtuins
Online Access:https://www.termedia.pl/The-role-of-ceramide-and-SEW-2871-in-the-transcription-of-enzymes-involved-in-amyloid-b-precursor-protein-metabolism-in-an-experimental-model-of-Alzheimer-s-disease,20,33884,1,1.html

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https://www.termedia.pl/The-role-of-ceramide-and-SEW-2871-in-the-transcription-of-enzymes-involved-in-amyloid-b-precursor-protein-metabolism-in-an-experimental-model-of-Alzheimer-s-disease,20,33884,1,1.html

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