Acute hemodynamics of cardiac sympathetic denervation

Introduction: We aimed to study the immediate hemodynamic effects of thoracoscopic bilateral cardiac sympathetic denervation (CSD) for recurrent ventricular tachycardia (VT) or VT storm. Method: We studied a group of 18 adults who underwent bilateral thoracoscopic CSD; the blood pressure (BP) and He...

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Bibliographic Details
Main Authors: Kunal Sinkar, Avishek Bagchi, Ankit Mahajan, Ramalingam Vadivelu, Meera Venkatraman, Reshma Motwani, Sanjeev Vichare, Suresh Joshi, Dinesh Parikh, Jude Vaz, Yash Lokhandwala
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Indian Pacing and Electrophysiology Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S0972629220300656
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Summary:Introduction: We aimed to study the immediate hemodynamic effects of thoracoscopic bilateral cardiac sympathetic denervation (CSD) for recurrent ventricular tachycardia (VT) or VT storm. Method: We studied a group of 18 adults who underwent bilateral thoracoscopic CSD; the blood pressure (BP) and Heart Rate (HR) were continuously monitored during the surgery and up to 6 h post-operatively. Results: Immediately on removal of the sympathetic ganglia, the patients had a drop in both the systolic (110 mm Hg to 95.8 mm Hg, p < 0.001) and diastolic BP (69.4 mm Hg to65 mm Hg, p = 0.007) along with a drop in the HR (81.6 bpm to 61.2 bpm, p < 0.001).At 6 h after CSD, the systolic and diastolic BP did not recover significantly, while there was recovery in HR (61.2 bpm to 66 bpm, p = 0.02). There was no significant difference between those with and without left ventricular (LV) systolic dysfunction. Conclusion: The acute hemodynamic changes during the perioperative period of CSD are significant but not serious. Awareness of this is useful for peri-operative management.
ISSN:0972-6292