Protein Kinase C Activation by Helicobacter pylori in Human Gastric Epithelial Cells Limits Interleukin-8 Production Through Suppression of Extracellular Signal-Regulated Kinase

Protein Kinase C Activation by Helicobacter pylori in Human Gastric Epithelial Cells Limits Interleukin-8 Production Through Suppression of Extracellular Signal-Regulated Kinase

Helicobacter pylori (H. pylori) infection of gastric epithelial cells has been shown to induce interleukin (IL)-8 production, but the signal transduction mechanism leading to IL-8 production has not been clearly defined. Here, we investigate the role of protein kinase C (PKC) in the mechanism of ind...

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Bibliographic Details
Main Authors: Yoshihisa Nozawa, Katsushi Nishihara, Yushiro Akizawa, Naoki Orimoto, Motoko Nakano, Tatsuya Uji, Hirofusa Ajioka, Atsuhiro Kanda, Naosuke Matsuura, Mamoru Kiniwa
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319324909

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