TLR1/2 orchestrate human plasmacytoid predendritic cell response to gram+ bacteria.

TLR1/2 orchestrate human plasmacytoid predendritic cell response to gram+ bacteria.

Gram+ infections are worldwide life-threatening diseases in which the pathological role of type I interferon (IFN) has been highlighted. Plasmacytoid predendritic cells (pDCs) produce high amounts of type I IFN following viral sensing. Despite studies suggesting that pDCs respond to bacteria, the me...

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Bibliographic Details
Main Authors:	Salvatore Raieli, Coline Trichot, Sarantis Korniotis, Lucia Pattarini, Vassili Soumelis
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2019-04-01
Series:	PLoS Biology
Online Access:	https://doi.org/10.1371/journal.pbio.3000209

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