Identification of an Evolutionarily Conserved Ankyrin Domain-Containing Protein, Caiap, Which Regulates Inflammasome-Dependent Resistance to Bacterial Infection

Identification of an Evolutionarily Conserved Ankyrin Domain-Containing Protein, Caiap, Which Regulates Inflammasome-Dependent Resistance to Bacterial Infection

Many proteins contain tandemly repeated modules of several amino acids, which act as the building blocks that form the underlying architecture of a specific protein-binding interface. Among these motifs and one of the most frequently observed is ankyrin repeats (ANK), which consist of 33 amino acid...

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Bibliographic Details
Main Authors: Sylwia D. Tyrkalska, Sergio Candel, Ana B. Pérez-Oliva, Ana Valera, Francisca Alcaraz-Pérez, Diana García-Moreno, María L. Cayuela, Victoriano Mulero
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Immunology
Subjects:
ankyrin repeats
inflammasome
macrophages
bacterial infection
flagellin
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01375/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01375/full

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