Protective Effects of Inducible HO-1 on Oxygen Toxicity in Rat Brain Endothelial Microvessel Cells

Protective Effects of Inducible HO-1 on Oxygen Toxicity in Rat Brain Endothelial Microvessel Cells

BackgroundReperfusion in ischemia is believed to generate cytotoxic oxidative stress, which mediates reperfusion injury. These stress conditions can initiate lipid peroxidation and damage to proteins, as well as promote DNA strand breaks. As biliverdin and bilirubin produced by heme oxygenase isofor...

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Bibliographic Details
Main Authors: Seung-Jun Yoo, Neal K. Nakra, Gabriele V. Ronnett, Cheil Moon
Format: Article
Language:English
Published: Academya Publishing Co. 2014-09-01
Series:Endocrinology and Metabolism
Subjects:
Heme
Oxygenases
Bilirubin
Iron
Carbon monoxide
Online Access:http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-29-356.pdf

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