Pluripotency factor binding and <it>Tsix </it>expression act synergistically to repress <it>Xist </it>in undifferentiated embryonic stem cells

<p>Abstract</p> <p>Background</p> <p>Expression of <it>Xist</it>, the master regulator of X chromosome inactivation, is extinguished in pluripotent cells, a process that has been linked to programmed X chromosome reactivation. The key pluripotency transcript...

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Bibliographic Details
Main Authors: Nesterova Tatyana B, Senner Claire E, Schneider Janina, Alcayna-Stevens Tilly, Tattermusch Anna, Hemberger Myriam, Brockdorff Neil
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Epigenetics & Chromatin
Online Access:http://www.epigeneticsandchromatin.com/content/4/1/17