Pluripotency factor binding and <it>Tsix </it>expression act synergistically to repress <it>Xist </it>in undifferentiated embryonic stem cells
<p>Abstract</p> <p>Background</p> <p>Expression of <it>Xist</it>, the master regulator of X chromosome inactivation, is extinguished in pluripotent cells, a process that has been linked to programmed X chromosome reactivation. The key pluripotency transcript...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-10-01
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Series: | Epigenetics & Chromatin |
Online Access: | http://www.epigeneticsandchromatin.com/content/4/1/17 |