| Summary: | AbstractAim: The
aim of this study was to evaluate the role of intermediate echo time (TE) Proton
Magnetic Resonance Spectroscopy (1 H-MRS) in the differential diagnosis of neoplastic
and nonneoplastic cerebral mass lesions.Materials and Methods: The
research was done at Cukurova University in a 1.5 Tesla whole-body MR system.
In point-resolved-single volume-spectroscopy (PRESS) localization method,
Probe-P pulse sequence was studied with intermediate TE (TE=144). Of 55 cases
whose diagnosis was confirmed with the histopathologically or clinical and
radiological follow-up, MR Spectroscopy
findings were discussed.Results: Twenty cases’ definite diagnosis
were neoplastic and thirty-five cases’ were nonneoplastic lesions. For tumor
detection in cerebral mass lesions, intermediate TE MRS was determined 100% sensitive and 91.7%
specific. The positive predictive value
was 86.4% and the negative one was 100%. In this study, in the neoplastic-nonneoplastic
lesion differential diagnosis, NAA/Cho, NAA/Cr, Cho/Cr, and Cho/NAA ratios were
evaluated and the most useful of them were found to be Cho/NAA ratio.
Conclusion: It is
concluded that intermediate TE MR Spectroscopy is a reliable imaging technique
for the neoplastic-nonneoplastic differential diagnosis of the cerebral mass
lesions.
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