Characteristics of Plasmablast Repertoire in Chronically HIV-Infected Individuals for Immunoglobulin H and L Chain Profiled by Single-Cell Analysis

Characteristics of Plasmablast Repertoire in Chronically HIV-Infected Individuals for Immunoglobulin H and L Chain Profiled by Single-Cell Analysis

Characterization of the diversified immunoglobulin (Ig) repertoire may provide insight into pathways that shape an efficient antibody (Ab) repertoire for immune response against human immunodeficiency virus (HIV) infection. This study aimed to profile characteristics of the plasmablast repertoire du...

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Bibliographic Details
Main Authors: Hongyan Liao, Song Li, Yangsheng Yu, Yinshi Yue, Kaihong Su, Qin Zheng, Nenggang Jiang, Zhixin Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
human immunodeficiency virus
plasmablast
repertoire
variable region
single-cell PCR
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.03163/full

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