Proteome-wide Prediction of Lysine Methylation Leads to Identification of H2BK43 Methylation and Outlines the Potential Methyllysine Proteome

Proteome-wide Prediction of Lysine Methylation Leads to Identification of H2BK43 Methylation and Outlines the Potential Methyllysine Proteome

Summary: Protein Lys methylation plays a critical role in numerous cellular processes, but it is challenging to identify Lys methylation in a systematic manner. Here we present an approach combining in silico prediction with targeted mass spectrometry (MS) to identify Lys methylation (Kme) sites at...

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Bibliographic Details
Main Authors: Kyle K. Biggar, Francois Charih, Huadong Liu, Yasser B. Ruiz-Blanco, Leanne Stalker, Anand Chopra, Justin Connolly, Hemanta Adhikary, Kristin Frensemier, Matthew Hoekstra, Marek Galka, Qi Fang, Christopher Wynder, William L. Stanford, James R. Green, Shawn S.-C. Li
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Cell Reports
Subjects:
lysine methylation
histone marks
histone H1
histone H2B
non-histone methylation
methyllysine proteome
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720308779

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http://www.sciencedirect.com/science/article/pii/S2211124720308779

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