Long noncoding RNA PM maintains cerebellar synaptic integrity and Cbln1 activation via Pax6/Mll1-mediated H3K4me3.

Long noncoding RNA PM maintains cerebellar synaptic integrity and Cbln1 activation via Pax6/Mll1-mediated H3K4me3.

Recent studies have shown that long noncoding RNAs (lncRNAs) are critical regulators in the central nervous system (CNS). However, their roles in the cerebellum are currently unclear. In this work, we identified the isoform 204 of lncRNA Gm2694 (designated as lncRNA-Promoting Methylation (lncRNA-PM)...

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Bibliographic Details
Main Authors: Yan Jin, Bowen Zhang, Junxia Lu, Yingdong Song, Wei Wang, Wei Zhang, Fanghong Shao, Meng Gong, Meiting Wang, Xiaolin Liang, Shuqin Li, Zhi Zhang, Ge Shan, Xiangting Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-06-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001297

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