Aortic remodelling and false lumen changes after the frozen elephant trunk technique using the thoraflex hybrid stented graft for aortic dissection

Abstract Background Despite the marked improvement in the aortic dissection repair techniques, residual dissected aorta with a patent false lumen remains an issue. So, the aim of our study is to observe the effect of inserting the Thoraflex Hybrid Graft on the aortic diameters in patients with type...

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Main Authors: Mostafa Mehanna, Moustafa Elhamami, Ahmed Abolkasem, Bassem Ramadan, Abdallah Almaghraby, Jorge Mascaro
Format: Article
Language:English
Published: SpringerOpen 2021-08-01
Series:The Egyptian Heart Journal
Subjects:
Online Access:https://doi.org/10.1186/s43044-021-00198-x
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spelling doaj-c0aeed5949dc437086c9b303bbf2f2ab2021-08-29T11:28:20ZengSpringerOpenThe Egyptian Heart Journal2090-911X2021-08-017311610.1186/s43044-021-00198-xAortic remodelling and false lumen changes after the frozen elephant trunk technique using the thoraflex hybrid stented graft for aortic dissectionMostafa Mehanna0Moustafa Elhamami1Ahmed Abolkasem2Bassem Ramadan3Abdallah Almaghraby4Jorge Mascaro5Department of Cardiac Surgery, University Hospital BirminghamDepartment of Cardiothoracic Surgery, Faculty of Medicine, Alexandria UniversityDepartment of Cardiothoracic Surgery, Faculty of Medicine, Alexandria UniversityDepartment of Cardiothoracic Surgery, Faculty of Medicine, Alexandria UniversityCardiology and Angiology Department, Alexandria UniversityDepartment of Cardiac Surgery, University Hospital BirminghamAbstract Background Despite the marked improvement in the aortic dissection repair techniques, residual dissected aorta with a patent false lumen remains an issue. So, the aim of our study is to observe the effect of inserting the Thoraflex Hybrid Graft on the aortic diameters in patients with type A aortic dissection involving the arch and descending aorta. Patients with type I aortic dissection who had aortic dissection repair using the Thoraflex Hybrid Graft in University Hospitals Birmingham were studied. Radiological assessment with computed tomography of the aorta was done at the level of the diaphragm to measure the true lumen, false lumen and total aortic diameters. Significance of change of diameters at early post-operative as compared to the pre-operative period was analysed. Results Eight cases were done in the acute setting, while 14 cases were done in the chronic setting. The ratio of true lumen to the total aortic diameter has significantly increased in the follow-up period as compared to the pre-operative period (P = 0.031). Whereas false lumen to total aortic diameter ratio has significantly decreased (P = 0.024). Subgroup analysis revealed that these changes were not significantly altered by whether the dissection was acute or chronic. Conclusions The Thoraflex Hybrid Graft will induce positive aortic remodelling with expansion of true lumen and will diminish the false lumen. But we could not find a significant difference between acute or chronic cases due to small sample size.https://doi.org/10.1186/s43044-021-00198-xTrue lumenFalse lumenThoraflexRemodelling
collection DOAJ
language English
format Article
sources DOAJ
author Mostafa Mehanna
Moustafa Elhamami
Ahmed Abolkasem
Bassem Ramadan
Abdallah Almaghraby
Jorge Mascaro
spellingShingle Mostafa Mehanna
Moustafa Elhamami
Ahmed Abolkasem
Bassem Ramadan
Abdallah Almaghraby
Jorge Mascaro
Aortic remodelling and false lumen changes after the frozen elephant trunk technique using the thoraflex hybrid stented graft for aortic dissection
The Egyptian Heart Journal
True lumen
False lumen
Thoraflex
Remodelling
author_facet Mostafa Mehanna
Moustafa Elhamami
Ahmed Abolkasem
Bassem Ramadan
Abdallah Almaghraby
Jorge Mascaro
author_sort Mostafa Mehanna
title Aortic remodelling and false lumen changes after the frozen elephant trunk technique using the thoraflex hybrid stented graft for aortic dissection
title_short Aortic remodelling and false lumen changes after the frozen elephant trunk technique using the thoraflex hybrid stented graft for aortic dissection
title_full Aortic remodelling and false lumen changes after the frozen elephant trunk technique using the thoraflex hybrid stented graft for aortic dissection
title_fullStr Aortic remodelling and false lumen changes after the frozen elephant trunk technique using the thoraflex hybrid stented graft for aortic dissection
title_full_unstemmed Aortic remodelling and false lumen changes after the frozen elephant trunk technique using the thoraflex hybrid stented graft for aortic dissection
title_sort aortic remodelling and false lumen changes after the frozen elephant trunk technique using the thoraflex hybrid stented graft for aortic dissection
publisher SpringerOpen
series The Egyptian Heart Journal
issn 2090-911X
publishDate 2021-08-01
description Abstract Background Despite the marked improvement in the aortic dissection repair techniques, residual dissected aorta with a patent false lumen remains an issue. So, the aim of our study is to observe the effect of inserting the Thoraflex Hybrid Graft on the aortic diameters in patients with type A aortic dissection involving the arch and descending aorta. Patients with type I aortic dissection who had aortic dissection repair using the Thoraflex Hybrid Graft in University Hospitals Birmingham were studied. Radiological assessment with computed tomography of the aorta was done at the level of the diaphragm to measure the true lumen, false lumen and total aortic diameters. Significance of change of diameters at early post-operative as compared to the pre-operative period was analysed. Results Eight cases were done in the acute setting, while 14 cases were done in the chronic setting. The ratio of true lumen to the total aortic diameter has significantly increased in the follow-up period as compared to the pre-operative period (P = 0.031). Whereas false lumen to total aortic diameter ratio has significantly decreased (P = 0.024). Subgroup analysis revealed that these changes were not significantly altered by whether the dissection was acute or chronic. Conclusions The Thoraflex Hybrid Graft will induce positive aortic remodelling with expansion of true lumen and will diminish the false lumen. But we could not find a significant difference between acute or chronic cases due to small sample size.
topic True lumen
False lumen
Thoraflex
Remodelling
url https://doi.org/10.1186/s43044-021-00198-x
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