Radiographic and histological evaluation of bisphosphonate alendronate and metotrexate effects on rat mandibles inoculated with Walker 256 carcinosarcoma Avaliação radiográfica e histológica do efeito do bisfosfonato alendronato e do metotrexato na mandíbula de ratos inoculados com carcinossarcoma 256 de Walker

Radiographic and histological evaluation of bisphosphonate alendronate and metotrexate effects on rat mandibles inoculated with Walker 256 carcinosarcoma Avaliação radiográfica e histológica do efeito do bisfosfonato alendronato e do metotrexato na mandíbula de ratos inoculados com carcinossarcoma 256 de Walker

PURPOSE: To investigate the effects of bisphosphosnate alendronate (ALD) and metotrexate (MTX) on an experimental model of Walker 256 carcinosarcoma developed in the oral cavity of rats. METHODS Walker 256 carcinosarcoma cell suspension (0,1 mL) containing 10(6) cell/mL was implanted in the alveoli...

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Bibliographic Details
Main Authors: Ana Paula Negreiros Nunes Alves, Cláudia do Ó Pessoa, Letícia Costa-Lotufo, Manoel Odorico Moraes Filho
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2007-12-01
Series:Acta Cirurgica Brasileira
Subjects:
Neoplasias Bucais
Experimentação Animal
Carcinoma 256 de Walker
Alendronato
Ratos
Mouth Neoplasms
Animal Experimentation
Carcinoma 256, Walker
Alendronate
Rats
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502007000600008

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