Demethylated miR-216a Regulates High Mobility Group Box 3 Promoting Growth of Esophageal Cancer Cells Through Wnt/β-Catenin Pathway

Demethylated miR-216a Regulates High Mobility Group Box 3 Promoting Growth of Esophageal Cancer Cells Through Wnt/β-Catenin Pathway

BackgroundEsophageal cancer (EC) is the eighth most common cause of cancer-associated mortality in humans. Recent studies have revealed the important roles of microRNAs (miRs) in mediating tumor initiation and progression. miR-216a has been found to be involved in the progression of EC, but the unde...

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Bibliographic Details
Main Authors: Cheng-Xi Sun, Feng Zhu, Lei Qi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
esophageal cancer
miR-216a
DNA methylation
HMGB3
Wnt/β-catenin pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.622073/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.622073/full

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