Catalytic asymmetric Nakamura reaction by gold(I)/chiral N,Nʹ-dioxide-indium(III) or nickel(II) synergistic catalysis

Catalytic asymmetric Nakamura reaction by gold(I)/chiral N,Nʹ-dioxide-indium(III) or nickel(II) synergistic catalysis

Although enols and enolates addition to unactivated alkynes is used for carbon-carbon bond modification a catalytic asymmetric alkyne with 1,3-dicarbonyl compound has been elusive. Here, the authors achieve this using the synergistic activation of chiral N,N′-dioxide-indium(III) or nickel(II) Lewis...

Full description

Bibliographic Details
Main Authors: Xinyue Hu, Xiaoxue Tang, Xiying Zhang, Lili Lin, Xiaoming Feng
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23105-z
id doaj-c0aa41cc7c1143b6bf4620373dab5bd5
record_format Article
spelling doaj-c0aa41cc7c1143b6bf4620373dab5bd52021-05-23T11:12:54ZengNature Publishing GroupNature Communications2041-17232021-05-0112111010.1038/s41467-021-23105-zCatalytic asymmetric Nakamura reaction by gold(I)/chiral N,Nʹ-dioxide-indium(III) or nickel(II) synergistic catalysisXinyue Hu0Xiaoxue Tang1Xiying Zhang2Lili Lin3Xiaoming Feng4Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan UniversityKey Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan UniversityKey Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan UniversityKey Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan UniversityKey Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan UniversityAlthough enols and enolates addition to unactivated alkynes is used for carbon-carbon bond modification a catalytic asymmetric alkyne with 1,3-dicarbonyl compound has been elusive. Here, the authors achieve this using the synergistic activation of chiral N,N′-dioxide-indium(III) or nickel(II) Lewis acid and achiral gold(I) π-acid.”https://doi.org/10.1038/s41467-021-23105-z
collection DOAJ
language English
format Article
sources DOAJ
author Xinyue Hu
Xiaoxue Tang
Xiying Zhang
Lili Lin
Xiaoming Feng
spellingShingle Xinyue Hu
Xiaoxue Tang
Xiying Zhang
Lili Lin
Xiaoming Feng
Catalytic asymmetric Nakamura reaction by gold(I)/chiral N,Nʹ-dioxide-indium(III) or nickel(II) synergistic catalysis
Nature Communications
author_facet Xinyue Hu
Xiaoxue Tang
Xiying Zhang
Lili Lin
Xiaoming Feng
author_sort Xinyue Hu
title Catalytic asymmetric Nakamura reaction by gold(I)/chiral N,Nʹ-dioxide-indium(III) or nickel(II) synergistic catalysis
title_short Catalytic asymmetric Nakamura reaction by gold(I)/chiral N,Nʹ-dioxide-indium(III) or nickel(II) synergistic catalysis
title_full Catalytic asymmetric Nakamura reaction by gold(I)/chiral N,Nʹ-dioxide-indium(III) or nickel(II) synergistic catalysis
title_fullStr Catalytic asymmetric Nakamura reaction by gold(I)/chiral N,Nʹ-dioxide-indium(III) or nickel(II) synergistic catalysis
title_full_unstemmed Catalytic asymmetric Nakamura reaction by gold(I)/chiral N,Nʹ-dioxide-indium(III) or nickel(II) synergistic catalysis
title_sort catalytic asymmetric nakamura reaction by gold(i)/chiral n,nʹ-dioxide-indium(iii) or nickel(ii) synergistic catalysis
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2021-05-01
description Although enols and enolates addition to unactivated alkynes is used for carbon-carbon bond modification a catalytic asymmetric alkyne with 1,3-dicarbonyl compound has been elusive. Here, the authors achieve this using the synergistic activation of chiral N,N′-dioxide-indium(III) or nickel(II) Lewis acid and achiral gold(I) π-acid.”
url https://doi.org/10.1038/s41467-021-23105-z
work_keys_str_mv AT xinyuehu catalyticasymmetricnakamurareactionbygoldichiralnnʹdioxideindiumiiiornickeliisynergisticcatalysis
AT xiaoxuetang catalyticasymmetricnakamurareactionbygoldichiralnnʹdioxideindiumiiiornickeliisynergisticcatalysis
AT xiyingzhang catalyticasymmetricnakamurareactionbygoldichiralnnʹdioxideindiumiiiornickeliisynergisticcatalysis
AT lililin catalyticasymmetricnakamurareactionbygoldichiralnnʹdioxideindiumiiiornickeliisynergisticcatalysis
AT xiaomingfeng catalyticasymmetricnakamurareactionbygoldichiralnnʹdioxideindiumiiiornickeliisynergisticcatalysis
_version_ 1721430110779736064

Similar Items