Diagnostic Value of Specific Markers in the Verification of Bacterial Nature of the Inflammatory Processes n the Respiratory System

Introduction. Recently, there are accumulated more data on the role of infection as a risk factor for wheezing syndrome, bronchial asthma (BA) and its exacerbations, which often calls for differential diagnosis with such complications, as pneumonia of bacterial or viral etiology. Objective of the st...

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Main Authors: O.K. Koloskova, L.A. Ivanova, T.M. Bіlous, R.I. Goncharuk
Format: Article
Language:English
Published: Publishing House Zaslavsky 2016-09-01
Series:Aktualʹnaâ Infektologiâ
Online Access:http://ai.zaslavsky.com.ua/article/view/81712
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spelling doaj-c088b0e47ba24b81924f200473a499652020-11-25T01:08:30ZengPublishing House ZaslavskyAktualʹnaâ Infektologiâ2312-413X2312-41482016-09-0143.12465110.22141/2312-413x.3.12.2016.8171281712Diagnostic Value of Specific Markers in the Verification of Bacterial Nature of the Inflammatory Processes n the Respiratory SystemO.K. Koloskova0L.A. Ivanova1T.M. Bіlous2R.I. Goncharuk3Higher State Educational Institution of Ukraine «Bukovynian State Medical University», ChernivtsiHigher State Educational Institution of Ukraine «Bukovynian State Medical University», ChernivtsiHigher State Educational Institution of Ukraine «Bukovynian State Medical University», ChernivtsiHigher State Educational Institution of Ukraine «Bukovynian State Medical University», ChernivtsiIntroduction. Recently, there are accumulated more data on the role of infection as a risk factor for wheezing syndrome, bronchial asthma (BA) and its exacerbations, which often calls for differential diagnosis with such complications, as pneumonia of bacterial or viral etiology. Objective of the study: in order to improve the diagnosis of bacterial inflammations of the airways in children of all ages to explore some results of the patients’ survey. Materials and methods. Comprehensively, we have examined 279 sick children, from infancy to the preschool age. The first (I) clinical group consisted of 100 infants, who were admitted to the hospital for community-acquired bacterial pneumonia (BP). The second (II) group included 56 children with asthma, in whom we have confirmed the bacterial nature of febrile asthma attacks. The third (III) group consisted of 46 BA patients with confirmed viral nature of febrile asthma exacerbations. The fourth (IV) group included 77 infants with acute respiratory viral infection (ARVI) in the form of acute bronchitis (45 children), bronchiolitis (15 cases) and viral pneumonia (17 patients). Results and their discussion. The white blood cell count of the peripheral blood revealed in patients with BP the presence of bacterial and inflammatory process in contrast to peers with ARVI. The study of C-reactive protein concentrations in the blood serum allowed us to obtain the following results: the average content of this protein and in I clinical group was 67.26 ± 4.90 mg/l, in IV group — 22.39 ± 4.40 mg/l, in II group — 56.2 ± 2.6 mg/l and in III comparison group— 28.8 ± 2.4 mg/l (PI : II, III, IV; II : III, IV < 0.05). Conclusions. Consequently, none of the studied clinical and paraclinical markers have an independent diagnostic value in confirming bacterial inflammation.http://ai.zaslavsky.com.ua/article/view/81712
collection DOAJ
language English
format Article
sources DOAJ
author O.K. Koloskova
L.A. Ivanova
T.M. Bіlous
R.I. Goncharuk
spellingShingle O.K. Koloskova
L.A. Ivanova
T.M. Bіlous
R.I. Goncharuk
Diagnostic Value of Specific Markers in the Verification of Bacterial Nature of the Inflammatory Processes n the Respiratory System
Aktualʹnaâ Infektologiâ
author_facet O.K. Koloskova
L.A. Ivanova
T.M. Bіlous
R.I. Goncharuk
author_sort O.K. Koloskova
title Diagnostic Value of Specific Markers in the Verification of Bacterial Nature of the Inflammatory Processes n the Respiratory System
title_short Diagnostic Value of Specific Markers in the Verification of Bacterial Nature of the Inflammatory Processes n the Respiratory System
title_full Diagnostic Value of Specific Markers in the Verification of Bacterial Nature of the Inflammatory Processes n the Respiratory System
title_fullStr Diagnostic Value of Specific Markers in the Verification of Bacterial Nature of the Inflammatory Processes n the Respiratory System
title_full_unstemmed Diagnostic Value of Specific Markers in the Verification of Bacterial Nature of the Inflammatory Processes n the Respiratory System
title_sort diagnostic value of specific markers in the verification of bacterial nature of the inflammatory processes n the respiratory system
publisher Publishing House Zaslavsky
series Aktualʹnaâ Infektologiâ
issn 2312-413X
2312-4148
publishDate 2016-09-01
description Introduction. Recently, there are accumulated more data on the role of infection as a risk factor for wheezing syndrome, bronchial asthma (BA) and its exacerbations, which often calls for differential diagnosis with such complications, as pneumonia of bacterial or viral etiology. Objective of the study: in order to improve the diagnosis of bacterial inflammations of the airways in children of all ages to explore some results of the patients’ survey. Materials and methods. Comprehensively, we have examined 279 sick children, from infancy to the preschool age. The first (I) clinical group consisted of 100 infants, who were admitted to the hospital for community-acquired bacterial pneumonia (BP). The second (II) group included 56 children with asthma, in whom we have confirmed the bacterial nature of febrile asthma attacks. The third (III) group consisted of 46 BA patients with confirmed viral nature of febrile asthma exacerbations. The fourth (IV) group included 77 infants with acute respiratory viral infection (ARVI) in the form of acute bronchitis (45 children), bronchiolitis (15 cases) and viral pneumonia (17 patients). Results and their discussion. The white blood cell count of the peripheral blood revealed in patients with BP the presence of bacterial and inflammatory process in contrast to peers with ARVI. The study of C-reactive protein concentrations in the blood serum allowed us to obtain the following results: the average content of this protein and in I clinical group was 67.26 ± 4.90 mg/l, in IV group — 22.39 ± 4.40 mg/l, in II group — 56.2 ± 2.6 mg/l and in III comparison group— 28.8 ± 2.4 mg/l (PI : II, III, IV; II : III, IV < 0.05). Conclusions. Consequently, none of the studied clinical and paraclinical markers have an independent diagnostic value in confirming bacterial inflammation.
url http://ai.zaslavsky.com.ua/article/view/81712
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