Influence of Static Magnetic Field Stimulation on the Accuracy of Tachystoscopically Presented Line Bisection

• Main Authors: Hikari Kirimoto, Tatsunori Watanabe, Nami Kubo, Shota Date, Toru Sunagawa, Tatsuya Mima, Katsuya Ogata, Hisato Nakazono, Shozo Tobimatsu, Antonio Oliviero
• Format: Article
• Language: English
• Published: MDPI AG 2020-12-01
• Series: Brain Sciences
• Subjects: transcranial static magnetic field stimulation; non-invasive brain stimulation; visuospatial cognition; unilateral spatial neglect
• Online Access: https://www.mdpi.com/2076-3425/10/12/1006

Transcranial static magnetic stimulation (tSMS) has been known to reduce human cortical excitability. Here, we investigated whether tSMS would modulate visuo-spatial cognition in healthy humans. Subjects performed a visuo-spatial task requiring judgements about the symmetry of pre-bisected lines. Visual stimuli consisted of symmetrically or asymmetrically transected lines, tachystoscopically presented for 150 ms on a computer monitor. Task performance was examined before, immediately after, and 10 min after tSMS/sham stimulation of 20 min over the posterior parietal cortex (PPC: P4 from the international 10–20 system) or superior temporal gyrus (STG: C6). Nine out of 16 subjects misjudged pre-bisected lines by consistently underestimating the length of the right-side segment (judging lines to be exactly pre-bisected when the transector was located to the left of the midpoint, or judging the left-side segment to be longer when the transector was located at the midpoint). In these subjects showing a leftward bias, tSMS over the right STG reduced the magnitude of the leftward bias. This did not occur with tSMS over the right PPC or sham stimulation. In the remaining right-biased subjects, no intervention effect was observed with any stimulation. Our findings indicate that application of tSMS over the right STG modulates visuo-spatial cognition in healthy adults.