Amino acid composition predicts prion activity.
Many prion-forming proteins contain glutamine/asparagine (Q/N) rich domains, and there are conflicting opinions as to the role of primary sequence in their conversion to the prion form: is this phenomenon driven primarily by amino acid composition, or, as a recent computational analysis suggested, d...
Main Authors: | Fayyaz Ul Amir Afsar Minhas, Eric D Ross, Asa Ben-Hur |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-04-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC5402983?pdf=render |
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