Amino acid composition predicts prion activity.

Many prion-forming proteins contain glutamine/asparagine (Q/N) rich domains, and there are conflicting opinions as to the role of primary sequence in their conversion to the prion form: is this phenomenon driven primarily by amino acid composition, or, as a recent computational analysis suggested, d...

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Bibliographic Details
Main Authors: Fayyaz Ul Amir Afsar Minhas, Eric D Ross, Asa Ben-Hur
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5402983?pdf=render