Plasticity of Paneth cells and their ability to regulate intestinal stem cells

Abstract Paneth cells (PCs) are located at the bottom of small intestinal crypts and play an important role in maintaining the stability of the intestinal tract. Previous studies reported on how PCs shape the intestinal microbiota or the response to the immune system. Recent studies have determined...

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Bibliographic Details
Main Authors: Xianglin Mei, Ming Gu, Meiying Li
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-020-01857-7