A Blood Biomarker for Duchenne Muscular Dystrophy Shows That Oxidation State of Albumin Correlates with Protein Oxidation and Damage in Mdx Muscle

A Blood Biomarker for Duchenne Muscular Dystrophy Shows That Oxidation State of Albumin Correlates with Protein Oxidation and Damage in Mdx Muscle

Duchenne muscular dystrophy (DMD) is a severe X-linked muscle wasting disease with no cure. While the precise mechanisms of progressive dystropathology remain unclear, oxidative stress caused by excessive generation of oxidants is strongly implicated. Blood biomarkers that could track oxidant levels...

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Bibliographic Details
Main Authors: Basma A. Al-Mshhdani, Miranda D. Grounds, Peter G. Arthur, Jessica R. Terrill
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Antioxidants
Subjects:
biomarkers
Cys34 albumin
thiol oxidation
oxidative stress
Duchenne muscular dystrophy
<i>mdx</i> mice
Online Access:https://www.mdpi.com/2076-3921/10/8/1241

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